COMPLEJO MULTI COLÁGENO PLUS 120 Cápsulas

What is this ingredient? This Multi Collagen Complex combines several collagen sources: hydrolyzed bovine hide, hydrolyzed fish collagen peptides, chicken bone broth collagen concentrate, and eggshell membrane collagen. Hydrolyzed collagen is collagen that has been broken into smaller peptides, which are more readily absorbed in the digestive tract. Multiple randomized, double‑blind, placebo‑controlled trials show that daily oral collagen peptides can improve skin hydration, elasticity, and wrinkle appearance in adult women, with benefits typically seen after 4–12 weeks of use [0,2,4,6,7,9].

Collagen peptides are also structural allies for joints and connective tissues. Clinical studies indicate that supplemental collagen can enhance muscle–tendon stiffness and explosive strength, and support joint comfort and function, likely by providing amino acids and signaling peptides that stimulate collagen synthesis in cartilage, tendons, and skin [5,8]. Using a mix of bovine, marine, poultry, and eggshell membrane collagen broadens the spectrum of collagen types and associated peptides supporting the body’s connective tissues.

Why include it in this formula? With vitamin C, biotin, hyaluronic acid, and a digestive enzyme blend, this product is clearly focused on supporting skin appearance, hair and nail integrity, and overall connective‑tissue health. The Multi Collagen Complex is the central "structural protein" pillar of the formula. It provides the primary building blocks and bioactive peptides that, in human trials, have been shown to enhance skin moisture, elasticity, smoothness, and markers of collagen renewal [0,2,4,6,7,9].

Vitamin C supports normal collagen formation, while hyaluronic acid contributes to skin hydration and joint lubrication. Biotin adds complementary support for keratin‑rich tissues like hair and nails. The digestive enzyme blend is included to help the body efficiently break down and utilize these proteins and co‑factors. Altogether, the Multi Collagen Complex anchors the product’s goal: promoting resilient, well‑hydrated skin and robust connective tissues from the inside out.

References

• [0] Oral intake of collagen peptide NS improves hydration, elasticity, desquamation, and wrinkling in human skin: a randomized, double-blinded, placebo-controlled study
• [2] Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study
• [5] Collagen Peptide Supplementation Enhances Muscle-Tendon Stiffness and Explosive Strength: A 16-Week Randomized Controlled Trial
• [6] Ingestion of bioactive collagen hydrolysates enhance facial skin moisture and elasticity and reduce facial ageing signs in a randomised double-blind placebo-controlled clinical study
• [9] Four-weeks daily intake of oral collagen hydrolysate results in improved skin elasticity, especially in sun-exposed areas: a randomized, double-blind, placebo-controlled trial

What is this ingredient? The Digestive Enzyme Blend in this formula is a composite ingredient that typically includes enzymes such as proteases, amylases, and lipases, and sometimes specific enzymes for fiber or lactose. These enzymes help break down large food molecules—proteins, carbohydrates, and fats—into smaller components the body can absorb more efficiently. In general, digestive enzymes support the normal digestive process, which can help reduce the burden on the gut when meals are rich in protein or complex foods.

By assisting the body’s own digestive secretions, such blends help ensure that nutrients like amino acids, vitamins, and other bioactives are released from food and supplements more effectively. While individual enzyme compositions vary, the unifying goal is to promote comfortable digestion and efficient nutrient uptake without acting as stimulants or laxatives.

Why include it in this formula? With a Multi Collagen Complex, vitamin C, biotin, and hyaluronic acid, this product is clearly focused on supporting skin, hair, nails, and overall connective‑tissue health from the inside out. The Digestive Enzyme Blend functions as a "utilization support" pillar. Collagen peptides, vitamin C, and hyaluronic acid are only as useful as the body’s ability to digest, absorb, and circulate them; enzymes help liberate amino acids and co‑factors from the protein‑rich collagen matrix.

By promoting smoother digestion of collagen and accompanying nutrients, the blend supports consistent delivery of the building blocks needed for collagen formation, skin hydration, and keratin structure. In practical terms, it helps the formula work more efficiently, so the structural and beauty‑focused ingredients are more available to the tissues they are intended to nourish.

What is this ingredient? Vitamin C is an essential, water‑soluble vitamin that humans must obtain from the diet. It serves as a key cofactor for several enzymes involved in collagen maturation, including prolyl and lysyl hydroxylases, which are required to convert raw collagen chains into stable, properly cross‑linked collagen fibers [1,3,6]. Without adequate vitamin C, the hydroxylation of proline and lysine in collagen stalls, compromising connective‑tissue integrity, as seen in classic vitamin C deficiency states. In addition, vitamin C functions as a potent antioxidant, helping to neutralize reactive oxygen species and protect lipids, proteins, and DNA from oxidative stress.

Clinical studies evaluating supplements that combine collagen peptides with vitamin C report improvements in dermal collagen structure, skin density, and visible signs of aging such as wrinkles and roughness over 8–16 weeks compared with placebo [0,2,9]. While these formulas often include multiple components, vitamin C is consistently included because of its central role in collagen synthesis and connective‑tissue maintenance.

Why include it in this formula? With Multi Collagen Complex, a Digestive Enzyme Blend, biotin, and hyaluronic acid, this product is clearly focused on supporting skin appearance, hair and nail integrity, and overall connective‑tissue health. Within this architecture, vitamin C acts as a "collagen activation and protection" pillar. Collagen peptides supply the raw amino acids, and vitamin C provides the enzymatic support needed for proper hydroxylation and cross‑linking of new collagen fibers in skin, cartilage, and other tissues [1,3,6].

Vitamin C’s antioxidant activity also helps shield existing collagen and hyaluronic acid in the skin from oxidative damage, complementing hyaluronic acid’s hydration benefits and biotin’s support for keratin‑rich tissues. Clinical collagen supplements that include vitamin C have shown meaningful improvements in skin structure, density, and wrinkle appearance, reinforcing this synergistic approach [0,2,9]. In this way, vitamin C ensures the formula does not just deliver collagen building blocks, but also the cofactor needed to turn them into well‑organized, resilient connective tissue.

References

• [0] The Effects of Dietary Supplementation with Collagen and Vitamin C and Their Combination with Hyaluronic Acid on Skin Density, Texture and Other Parameters: A Randomised, Double-Blind, Placebo-Controlled Trial
• [1] Effects of L-ascorbic acid (Vit-C) on collagen amino acids: DFT study
• [2] A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study
• [3] Ascorbic acid promotes a TGFβ1-induced myofibroblast phenotype switch
• [9] A Clinical Trial Shows Improvement in Skin Collagen, Hydration, Elasticity, Wrinkles, Scalp, and Hair Condition following 12-Week Oral Intake of a Supplement Containing Hydrolysed Collagen

What is this ingredient? Biotin is a water‑soluble B vitamin that serves as a cofactor for several carboxylase enzymes involved in fatty acid synthesis, gluconeogenesis, and amino acid metabolism [0,6]. These enzymes help the body generate energy and build lipid structures, including those found in skin and its appendages. True biotin deficiency is uncommon, but when it occurs it typically presents with gradual onset of fatigue, hair thinning or alopecia, brittle or abnormal nails, and eczematous skin rashes, and can progress to neurological symptoms if uncorrected [3].

In the context of hair and nail concerns, a review of clinical evidence suggests that biotin supplementation can be beneficial mainly in people with clearly documented deficiency or specific nail or hair disorders such as brittle nail syndrome or uncombable hair; robust data in otherwise well‑nourished individuals remain limited [2,8,9]. Still, because biotin-dependent enzymes are central to fatty acid and keratin infrastructure, this vitamin is widely used in beauty‑focused supplements despite the evidence gaps.

Why include it in this formula? With its combination of a Multi Collagen Complex, vitamin C, hyaluronic acid, a digestive enzyme blend, and biotin, this product is clearly designed to support the appearance and structure of skin, hair, nails, and other connective tissues. Within that architecture, biotin serves as the "keratin and lipid metabolism" pillar. While collagen peptides and vitamin C focus on collagen networks, biotin supports the enzymatic machinery that underpins fatty acid production and keratin formation in hair shafts and nail plates [0,6,9].

This makes biotin a logical complement to collagen and hyaluronic acid: collagen helps provide tensile strength; hyaluronic acid supports hydration and plumpness; and biotin helps ensure that hair and nails have the metabolic support they need to grow with a healthy structure. Even though high‑dose biotin is not a cure‑all for cosmetic concerns, maintaining adequate biotin status fits the product’s inside‑out approach to beauty and structural resilience, especially when combined with targeted structural nutrients.

References

• [0] The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
• [3] Biotin Deficiency
• [8] Dietary supplements in dermatology: A review of the evidence for zinc, biotin, vitamin D, nicotinamide, and Polypodium
• [9] Vitamins and minerals: their role in nail health and disease

What is this ingredient? Hyaluronic acid is a naturally occurring glycosaminoglycan found in high concentrations in the skin, joint fluid, and other connective tissues. It has a remarkable capacity to bind and retain water, helping to maintain tissue hydration, plumpness, and mechanical cushioning. As we age, endogenous hyaluronic acid levels in the skin decline, contributing to dryness, fine lines, and loss of elasticity.

Several randomized, double‑blind, placebo‑controlled trials have shown that oral hyaluronic acid can improve key skin parameters. Daily supplementation with low‑molecular‑weight or full‑spectrum hyaluronan for 4–12 weeks has been reported to increase stratum corneum hydration, reduce transepidermal water loss, and decrease wrinkle depth and volume compared with placebo [0,2–5]. Participants typically also show improvements in skin smoothness, brightness, and overall appearance, supporting hyaluronic acid’s role as a true internal skin‑moisturizing agent.

Why include it in this formula? With Multi Collagen Complex, vitamin C, biotin, and a Digestive Enzyme Blend, this product is clearly designed to support skin appearance, hair and nail strength, and overall connective‑tissue health. Within that framework, hyaluronic acid is the "deep hydration and plumping" pillar. While collagen peptides and vitamin C focus on building and cross‑linking collagen fibers, hyaluronic acid fills the spaces between those fibers with water‑rich gel, helping skin look smoother, fuller, and less lined [0,2–5].

Clinical studies of oral hyaluronic acid supplements have demonstrated significant gains in skin hydration, elasticity, and wrinkle reduction over 4–12 weeks, complementing the structural support provided by collagen and the keratin support from biotin [0,2–5]. By combining hyaluronic acid with collagen, this formula addresses both the scaffold and the moisture matrix of the skin, aligning with its goal of promoting supple, resilient, and youthful‑looking skin from within.

References

• [0] Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study
• [2] Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period
• [4] Oral intake of a new full-spectrum hyaluronan improves skin profilometry and ageing: a randomized, double-blind, placebo-controlled clinical trial
• [5] Oral administration of hyaluronic acid to improve skin conditions via a randomized double-blind clinical test